Work involves biologists and chemists and attained international recognition
UA offers new solution to deactivate multiresistant bacteria in sewage
Da esq. para a dt.: José Cavaleiro, Amparo Faustino, Augusto Tomé, Ângela Cunha, Graça Neves, Eliana Alves e Adelaide Almeida
In order to look for for a solution to bacterial resistance to multiple antibiotics, an increasingly serious threat to public health, a multidisciplinary team from the University of Aveiro has been working on new applications for methods used in other scientific areas. One such method, the photodynamic inactivation has been tested in the treatment of hospital sewerage, where these multidrug-resistant bacteria are often found and, according to studies conducted so far, appears to be much more effective than other conventional approaches. Several articles published in this area achieved national and international recognition.

Photodynamic therapy is a method already used in the treatment of certain types of cancer and is now being tested in hospital treatment of these effluents. It basically consists in using " photosensitizers " as porphyrins , phthalocyanines , chlorins and some dyes , which absorb visible light and transfer energy to molecules around it, resulting in reactive oxygen species which are highly cytotoxic, causing change in the biomolecules (proteins , lipids and nucleic acids ) in these pathogens , leading to their inactivation .

The team, coordinated by Adelaide Almeida, involves researchers from the Department of Biology, the Centre for Environmental and Marine Studies (CESAM), and the Department of Chemistry, specifically the Organic Chemistry, Natural Products and Food Stuffs (QOPNA).

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